Shiga Toxin-Mediated Disease in MyD88-Deficient Mice Infected with Escherichia coli O157:H7

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in <i>Tlr4</i> Gene

Alexander Poltorak, Xiaolong He, Irina Smirnova et al. · Science · 1998 · 7.6K citations

Life Sciences, Immunology, Molecular Biology +17

Recognition of Commensal Microflora by Toll-Like Receptors Is Required for Intestinal Homeostasis

Seth Rakoff-Nahoum, Justin C. Paglino, Fatima Eslami-Varzaneh et al. · Cell · 2004 · 4.2K citations · Full text

Life Sciences, Immunology, Microbiology +16

Cutting Edge: Toll-Like Receptor 4 (TLR4)-Deficient Mice Are Hyporesponsive to Lipopolysaccharide: Evidence for TLR4 as the <i>Lps</i> Gene Product

Katsuaki Hoshino, Osamu Takeuchi, Taro Kawai et al. · The Journal of Immunology · 1999 · 3.4K citations · Full text

Life Sciences, Genetics, Immunology +15

Targeted Disruption of the MyD88 Gene Results in Loss of IL-1- and IL-18-Mediated Function

Osamu Adachi, Taro Kawai, Kiyoshi Takeda et al. · Immunity · 1998 · 2K citations · Full text

Life Sciences, Immunology, Molecular Biology +14

The Association Between Idiopathic Hemolytic Uremic Syndrome and Infection by Verotoxin-Producing Escherichia coli

Mohamed A. Karmali, M. Petric, Corazon Lim et al. · The Journal of Infectious Diseases · 1985 · 1.4K citations

Life Sciences, Microbiology, Nephrology +12