Peroxisome Proliferator-Activated Receptor-α Activation Promotes Macrophage Reverse Cholesterol Transport Through a Liver X Receptor–Dependent Pathway - Concepedia

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Peroxisome Proliferator-Activated Receptor-α Activation Promotes Macrophage Reverse Cholesterol Transport Through a Liver X Receptor–Dependent Pathway

DOI Full Paper Access

54

Citations

34

References

2011

Year

Kazuhiro Nakaya, Junichiro Tohyama, Snehal Naik, Hiroyuki Tanigawa, Colin H. Macphee, Jeffrey T. Billheimer, Daniel J. Rader

Arteriosclerosis Thrombosis and Vascular Biology

Abstract

Our observations demonstrate that a potent PPARα agonist promotes macrophage RCT in vivo in a manner that is enhanced by human apoA-I expression and dependent on both macrophage PPARα and LXR expression.

References

	Year	Citations

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