Novel Neuroprotective Mechanisms of Memantine: Increase in Neurotrophic Factor Release from Astroglia and Anti-Inflammation by Preventing Microglial Activation

Systemic LPS causes chronic neuroinflammation and progressive neurodegeneration

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Memantine in Moderate-to-Severe Alzheimer's Disease

‌Barry Reisberg, Rachelle S. Doody, Albrecht Stöffler et al. · New England Journal of Medicine · 2003 · 2K citations · Full text

Epilepsy and Exacerbation of Brain Injury in Mice Lacking the Glutamate Transporter GLT-1

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Structures of a histone deacetylase homologue bound to the TSA and SAHA inhibitors

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BDNF mRNA is decreased in the hippocampus of individuals with Alzheimer's disease

Heidi Phillips, Jeanne M. Hains, Mark Armanini et al. · Neuron · 1991 · 917 citations

Alzheimer's Disease, Bdnf Mrna, Dementia +8