Critical roles of the TGF-β type I receptor ALK5 in perichondrial formation and function, cartilage integrity, and osteoblast differentiation during growth plate development

The Novel Zinc Finger-Containing Transcription Factor Osterix Is Required for Osteoblast Differentiation and Bone Formation

Kazuhisa Nakashima, Xin Zhou, Gary R. Kunkel et al. · Cell · 2002 · 3.6K citations · Full text

Medicine, Genetics, Molecular Genetics +13

Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death.

A B Kulkarni, C G Huh, Daniel M. Becker et al. · Proceedings of the National Academy of Sciences · 1993 · 2K citations

Life Sciences, Immunology, Pathology +16

SB-431542 Is a Potent and Specific Inhibitor of Transforming Growth Factor-β Superfamily Type I Activin Receptor-Like Kinase (ALK) Receptors ALK4, ALK5, and ALK7

Gareth J. Inman, Francisco José Nicolás, James F. Callahan et al. · Molecular Pharmacology · 2002 · 1.7K citations

Life Sciences, Molecular Biology, Pharmacology +13

TGFβ2 knockout mice have multiple developmental defects that are non-overlapping with other TGFβ knockout phenotypes

Lynn Sanford, Ilona Ormsby, Adriana C. Gittenberger–de Groot et al. · Development · 1997 · 1.4K citations · Full text

Life Sciences, Developmental Biology, Molecular Genetics +17

Efficient Recombination in Diverse Tissues by a Tamoxifen-Inducible Form of Cre: A Tool for Temporally Regulated Gene Activation/Inactivation in the Mouse

Shigemi Hayashi, Andrew P. McMahon · Developmental Biology · 2002 · 1.4K citations

Medicine, Genetics, Molecular Genetics +17