A haplotype of the methylenetetrahydrofolate reductase gene predicts poor tumor response in rectal cancer patients receiving preoperative chemoradiation - Concepedia

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A haplotype of the methylenetetrahydrofolate reductase gene predicts poor tumor response in rectal cancer patients receiving preoperative chemoradiation

56

Citations

38

References

2006

Year

Salvatore Terrazzino, Marco Agostini, Salvatore Pucciarelli, Lara Maria Pasetto, Maria Luisa Friso, Alessandro Ambrosi, Veronica Lisi, Alberta Leon, Mario Lise, Donato Nitti

Pharmacogenetics and Genomics

Abstract

Unlike TS VNTR and SNP polymorphisms, MTHFR 677T-1298A haplotype in genomic DNA has the potential to be a predictive marker of tumor response in rectal cancer patients submitted to preoperative chemoradiotherapy.

References

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