Publication | Open Access
A general model for genetic recombination.
892
Citations
25
References
1975
Year
BiologyLinkage DisequilibriumMedicineGeneticsEvolutionary BiologyNatural SciencesDna ReplicationGenetic MechanismMolecular GeneticsGenetic VariationStrand ExchangeRecombination DynamicChromosomal RearrangementPopulation GeneticsGeneral ModelGene Transfer
A general model is proposed for genetic recombination. Its essential new feature is the hypothesis that recombination is initiated by a single-strand (or asymmetric) transfer, which may, after isomerization, become a two-strand (or symmetric) exchange. The likelihood of this transition from asymmetric to symmetric strand exchange determines certain characteristic features of recombination in any particular organism.
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