Concepedia

Publication | Open Access

Ligand-Activated Peroxisome Proliferator–Activated Receptor-γ Protects Against Ischemic Cerebral Infarction and Neuronal Apoptosis by 14-3-3ε Upregulation

DOIFull Paper Access

113

Citations

30

References

2009

Year

Jui‐Sheng Wu, Wai-Mui Cheung, Yau-Sheng Tsai, Yi-Tong Chen, Wen-Hsuan Fong, Hsin-Da Tsai, Yu‐Chang Chen, Jun‐Yang Liou, Song‐Kun Shyue, Jin-Jer Chen,
Circulation

Abstract

Ligand-activated PPAR-gamma confers resistance to neuronal apoptosis and cerebral infarction by driving 14-3-3epsilon transcription. 14-3-3epsilon Upregulation enhances sequestration of phosphorylated Bad and thereby suppresses apoptosis.

References

YearCitations

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