Caldesmon‐induced inhibition of ATPase activity of actomyosin and contraction of skinned fibres of chicken gizzard smooth muscle

Abstract

Caldesmon induces inhibition of MG2+-ATPase activity of actomyosin and relaxation of skinned fibers of chicken gizzard smooth muscle without influencing the level of myosin light chain-1 phosphorylation. Both these effects are reversed by calmodulin at a high molar excess over caldesmon in the presence of Ca2+.