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HIV-1 proviral DNA polymerase chain reaction detection in chorionic villi after exclusion of maternal contamination by variable number of tandem repeats analysis

DOI

38

Citations

0

References

1996

Year

C. Andreis, Giuseppe Simoni, Franca Rossella, C. Castagna, Elena Pesenti, Giovanni Porta, Giuseppe Colucci, S. Giuntelli, Giorgio Pardi, A.E. Semprini
AIDS

Abstract

Our study indicates that HIV-1 can infect the placenta from first trimester onwards. HIV was found in two-thirds of our cord blood samples but it is possible that some viral DNA in cord blood may have come from infected placental cells. Additional studies are needed to assess the source of HIV in cord blood and the possible contribution of placental or maternal cells infected with HIV to vertical transmission of the virus.