Publication | Open Access
Synthesis of Dehydrodeoxypodophyllotoxin Cyclic Ether via Allene Intramolecular Cycloaddition Strategy and Evaluation of Its Cytotoxicity
10
Citations
0
References
1991
Year
Natural Product SynthesisEngineeringHeterocyclicBiochemistryAlkene MetathesisNatural SciencesCyclic EtherOrganic ChemistryStereoselective SynthesisChemistryPharmacologyDehydrodeoxypodophyllotoxin Cyclic EtherEnantioselective SynthesisBiomolecular EngineeringNew RoutePropargyl Ether
The new route to dehydrodeoxypodophyllotoxin cyclic ether (10) has been realized via allene intramolecular Diels-Alder reaction of the propargyl ether (8)