Palladium N-heterocyclic carbene catalyzed regioselective C–H halogenation of 1-aryl-3-methyl-1H-pyrazol-5(4H)-ones using N-halosuccinimides (NXS)

Abstract

A novel palladium<italic>N</italic>-heterocyclic carbene complex of vitamin B₁was prepared and employed for regioselective C–H halogenation of 1-aryl-3-methyl-1<italic>H</italic>-pyrazol-5(4<italic>H</italic>)-ones using<italic>N</italic>-halosuccinimides.