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Synthetic enzymes. Part 2. Catalytic asymmetric epoxidation by means of polyamino-acids in a triphase system
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1982
Year
EngineeringOrganic ChemistryChemistryEnzymatic ModificationTriphase SystemBiochemical EngineeringSynthetic EnzymesStereoselective SynthesisCatalytic AmountsAsymmetric EpoxidationBiochemistryBiocatalysisCatalytic Asymmetric EpoxidationCatalysisAsymmetric CatalysisEnantioselective SynthesisBiomolecular EngineeringAlkene MetathesisNatural SciencesEnzyme CatalysisSynthetic Chemistry
The asymmetric epoxidation of several chalcones and other electron-poor olefins, in the presence of catalytic amounts of poly-(S)-amino-acids in a triphase system with optical yields of up to 96% is described. The influence of the molecular structure of the catalysts and substrates, the solvent, and the temperature on the stereochemistry is discussed.