Roles of the<i>ALDH2</i>and<i>ADH1B</i>Genotypes on the Association Between Alcohol Intake and Serum Adiponectin Levels Among Japanese Male Workers

Abstract

High alcohol consumption was inversely associated with T-Ad, HMW-Ad, and LMW-Ad levels in those with ADH1B *2/*2 genotype, but not in those with the other ADH1B genotypes. To our knowledge, this is the first study that reports combined effects of the alcohol-related polymorphisms and alcohol intake on serum adiponectin levels. Additional studies are required to confirm the present finding.