Retinoid Receptor Expression and all- <i>trans</i> Retinoic Acid–Mediated Growth Inhibition in Vascular Smooth Muscle Cells

Abstract

These results establish the presence of functional retinoid receptors in SMCs and document the growth-inhibitory action of atRA on these cells. Retinoid compounds, already in clinical use as antiproliferative agents for nonvascular indications, should be assessed further in in vivo models of intimal disease.