Electrocatalytic Reduction of Nitric Oxide at Electrodes Modified with Electropolymerized Films of [Cr(v-tpy)₂]³⁺and Their Application to Cellular NO Determinations

Abstract

Nitric oxide can be electrocatalytically reduced at electrodes modified with electropolymerized films of [Cr(v-tpy)2]3+. Upon further modification with a thin film of Nafion (to prevent interferences from anions, especially nitrite), these electrodes can be employed as NO sensors in solution with submicromolar detection limits and fast response. We have carried out preliminary studies of cellular NO release from Rhodobacter sphaeroides bacterial cells with excellent results.