Topical Amphotericin B and Subconjunctival Injection of Fluconazole (Combination Therapy) Versus Topical Amphotericin B (Monotherapy) in Treatment of Keratomycosis

Abstract

Combination therapy of topical amphotericin B eye drops with subconjunctival injection of fluconazole was more efficient (according to the percentage and the duration of healing of the ulcers) than the use of topical amphotericin B eye drops alone in dealing with cases of fungal keratitis--it may be contributed to the broad spectrum of the antifungal agents of the combination therapy than the monotherapy.