Hypervalent iodine-induced oxidative nucleophilic additions to alkenes: a novel acetoxy thiocyanation reaction in 1,1,1,3,3,3-hexafluoropropan-2-ol

Abstract

The combination of [bis(acetoxy)iodo]benzene and thiocyanate anion in a polar, protic non nucleophilic solvent such as 1,1,1,3,3,3-hexafluoropropan-2-ol is able to perform an oxidative nucleophilic addition to alkenes, leading to acetoxy thiocyanate derivatives, stereoselectively and with good regioselectivity.