IL-10 Promotes Production of Intestinal Mucus by Suppressing Protein Misfolding and Endoplasmic Reticulum Stress in Goblet Cells

Interleukin-10-deficient mice develop chronic enterocolitis

Ralf Kühn, Jürgen Löhler, D Rennick et al. · Cell · 1993 · 4.3K citations

Veterinary Medicine, Immunology, Infectious Diseases +14

Immunol. Cell Biol.

Melinda Fitzgerald, Ian P. Hayward, Anita C. Thomas et al. · 1995 · 2.6K citations

XBP1 Links ER Stress to Intestinal Inflammation and Confers Genetic Risk for Human Inflammatory Bowel Disease

Arthur Kaser, Ann–Hwee Lee, André Franke et al. · Cell · 2008 · 1.4K citations · Full text

Life Sciences, Genetics, Molecular Genetics +16

IRE1α Induces Thioredoxin-Interacting Protein to Activate the NLRP3 Inflammasome and Promote Programmed Cell Death under Irremediable ER Stress

Alana G. Lerner, John-Paul Upton, Paurush Praveen et al. · Cell Metabolism · 2012 · 832 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Interleukin (IL)-10 Inhibits Nuclear Factor кB (NFкB) Activation in Human Monocytes

Peng Wang, Ping Wu, Marvín I. Siegel et al. · Journal of Biological Chemistry · 1995 · 711 citations · Full text

Life Sciences, Cell Biology, Immunology +16