Progressive Soft Tissue Uptake of Tc-99m MDP Reflecting Metastatic Microcalcification

ROBIN D. LOW, Rodney J. Hicks, Barry Arkles, Gary D. Gill, W. R. Adam

Clinical Nuclear Medicine · 1992 · 15 citations · 0 references

Concepts

Abstract

A 49-year-old woman had longstanding renal impairment. Markedly increased uptake of Tc-99m MDP in the heart, lungs, and kidneys was an incidental finding on bone scintigraphy performed to exclude metastatic bone disease. These findings persisted on repeat bone imaging 1 year later. In addition, gastric and skeletal muscle uptake was subsequently seen. Soft tissue microcalcification was confirmed by computed tomography and renal biopsy. A consideration of the differential diagnosis is presented.