Allogeneic Mesenchymal Stem Cell Transplantation in Postinfarcted Rat Myocardium

Abstract

Allogeneic MSCs survive in infarcted myocardium as long as 6 months and express markers that suggest muscle and endothelium phenotypes. MSCs improved global LV function at 4 weeks; however, this benefit was transient, which suggests a possible early paracrine effect.