KIF1A missense mutations in SPG30, an autosomal recessive spastic paraplegia: distinct phenotypes according to the nature of the mutations

A structural change in the kinesin motor protein that drives motility

Sarah E. Rice, Abel W. Lin, Daniel Safer et al. · Nature · 1999 · 811 citations

Life Sciences, Biochemistry, Molecular Biology +14

A Kinesin Heavy Chain (KIF5A) Mutation in Hereditary Spastic Paraplegia (SPG10)

Evan Reid, Mark Kloos, Allison E. Ashley‐Koch et al. · The American Journal of Human Genetics · 2002 · 540 citations · Full text

Life Sciences, Neurology, Neuroscience +13

The Directional Preference of Kinesin Motors Is Specified by an Element outside of the Motor Catalytic Domain

Ryan Case, Daniel W. Pierce, Nora Hom-Booher et al. · Cell · 1997 · 360 citations · Full text

Life Sciences, Kinesiology, Motor Control +11

Defect in Synaptic Vesicle Precursor Transport and Neuronal Cell Death in KIF1A Motor Protein–deficient Mice

Yoshiaki YONEKAWA, Akihiro Harada, Yasushi Okada et al. · The Journal of Cell Biology · 1998 · 325 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Mutations in SPG11 are frequent in autosomal recessive spastic paraplegia with thin corpus callosum, cognitive decline and lower motor neuron degeneration

Giovanni Stévanin, Hamid Azzedine, Paola S. Denora et al. · Brain · 2007 · 253 citations

Life Sciences, Genetics, Neurology +17