Temporal relationship between bone loss and increased bone turnover in ovariectomized rats

Relationships between surface, volume, and thickness of iliac trabecular bone in aging and in osteoporosis. Implications for the microanatomic and cellular mechanisms of bone loss.

A. M. Parfitt, Catharina H. E. Mathews, A. R. Villanueva et al. · Journal of Clinical Investigation · 1983 · 1.5K citations · Full text

Medicine, Orthopaedic Surgery, Orthopedic Surgery +17

The mechanostat: a proposed pathogenic mechanism of osteoporoses and the bone mass effects of mechanical and nonmechanical agents.

Harold M. Frost · PubMed · 1987 · 618 citations

Natural Sciences, Orthopedic Surgery, Physiology +16

Menopausal changes in bone remodeling.

Robert P. Heaney, Robert R. Recker, Paul D. Saville · PubMed · 1978 · 437 citations

Medicine, Endocrinology, Gynecology +13

Skeletal alterations in ovariectomized rats

Thomas J. Wronski, P. L. Lowry, C. C. Walsh et al. · Calcified Tissue International · 1985 · 375 citations

Medicine, Endocrinology, Physiology +14

Histologic evidence for osteopenia and increased bone turnover in ovariectomized rats

Thomas J. Wronski, C. C. Walsh, L. A. Ignaszewski · Bone · 1986 · 317 citations

Medicine, Endocrinology, Bone Metabolism +14