Concepedia

Pharmacological Inhibition of CB1Cannabinoid Receptor Protects Against Doxorubicin-Induced Cardiotoxicity

Partha Mukhopadhyay, Sándor Bátkai, Mohanraj Rajesh, Nora Czifra, Judith Harvey‐White, György Haskó, Zsuzsanna K. Zsengellér, Norma P. Gerard, Lucas Liaudet, George Kunos,

Journal of the American College of Cardiology · 2007 · 207 citations · 21 references

DOIFull text

Open access

Concepts

References

21

Effects of Rimonabant on Metabolic Risk Factors in Overweight Patients with Dyslipidemia

Jean‐Pierre Després, Alain Golay, Lars Sjöström · New England Journal of Medicine · 2005 · 1.4K citations · Full text

, , +10

Effect of Rimonabant, a Cannabinoid-1 Receptor Blocker, on Weight and Cardiometabolic Risk Factors in Overweight or Obese Patients

F. Xavier Pi‐Sunyer, Louis J. Aronne, Hassan Heshmati et al. · JAMA · 2006 · 1.2K citations

, , +17

Adriamycin: The Role of Lipid Peroxidation in Cardiac Toxicity and Tumor Response

Charles E. Myers, William P. McGuire, Robert H. Liss et al. · Science · 1977 · 1.1K citations

, , +16

Redox cycling of anthracyclines by cardiac mitochondria. II. Formation of superoxide anion, hydrogen peroxide, and hydroxyl radical.

James H. Doroshow, Kelvin J.A. Davies · Journal of Biological Chemistry · 1986 · 549 citations · Full text

, , +17

Doxorubicin treatment in vivo causes cytochrome C release and cardiomyocyte apoptosis, as well as increased mitochondrial efficiency, superoxide dismutase activity, and Bcl-2:Bax ratio.

April C. Childs, Sharon Phaneuf, Amie J. Dirks et al. · PubMed · 2002 · 452 citations

, , +7