Halogen‐Bond‐Induced Activation of a Carbon–Heteroatom Bond

Abstract

I⋅⋅⋅Br-idging: Benzhydryl bromide can be activated by novel halogen-bond donors and subsequently undergoes a Ritter-like reaction with acetonitrile (see scheme). Comparative experiments with non-iodinated reference compounds and tests with added acids indicate that halogen bonds are very likely the basis for this effect. The activation seems to be applicable to other substrates as well.