Comparative Study on the Synergistic Action of Differentially Synthesized Silver Nanoparticles with <b><i>β</i></b>-Cephem Antibiotics and Chloramphenicol

Abstract

Synergistic activity of cephem antibiotics with silver nanoparticles (Ag NPs) was investigated. Silver nanoparticles were synthesized through biological and chemical method. The combined action of β -lactam cephem antibiotics with both green and chemically synthesized silver nanoparticles enhances the antibacterial activity against wide range of antibiotic resistant pathogens and making them applicable to medical devices and microbial control systems. Synergistic activity of chloramphenicol with silver nanoparticles was also studied.