Publication | Open Access
Sparse dynamic programming I
158
Citations
24
References
1992
Year
Mathematical ProgrammingEngineeringComputational ComplexityGenomicsSequence AlignmentSequence DesignString ProcessingCombinatorial OptimizationRna Structure PredictionSequence AnalysisComputer ScienceFunctional GenomicsBioinformaticsSparse Dynamic ProgrammingBiologyOptimization ProblemComputational BiologySparse Set MattersDynamic ProgrammingTime ComplexityDifferent Recurrence EquationsSystems BiologyMedicineDynamic Optimization
Dynamic programming solutions to a number of different recurrence equations for sequence comparison and for RNA secondary structure prediction are considered. These recurrences are defined over a number of points that is quadratic in the input size; however only a sparse set matters for the result. Efficient algorithms for these problems are given, when the weight functions used in the recurrences are taken to be linear. The time complexity of the algorithms depends almost linearly on the number of points that need to be considered; when the problems are sparse this results in a substantial speed-up over known algorithms.
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