Chronic Obstructive Pulmonary Disease: Safety and Tolerability of Hyperpolarized¹²⁹Xe MR Imaging in Healthy Volunteers and Patients

Abstract

Inhalation of hyperpolarized (129)Xe is well tolerated in healthy subjects and in those with mild or moderate COPD. Subjects do experience mild, transient, xenon-related symptoms, consistent with its known anesthetic properties.