INCREASED EXPRESSION OF MUC18 CORRELATES WITH THE METASTATIC PROGRESSION OF MOUSE PROSTATE ADENOCARCINOMA IN THE TRAMP MODEL

Abstract

MUC18 expression is up-regulated in the TRAMP model and it correlates with the malignant progression of mouse prostate adenocarcinoma in this transgenic model. This further strengthens the hypothesis that MUC18 has an important role in increasing the metastatic potential of prostate cancer cells.