Neutrophil myeloperoxidase measurements in plasma, laminar tissue, and skin of horses given black walnut extract

Abstract

In horses, BWHE administration causes increases in MPO concentration and activity in laminar tissue and skin and the time of increased MPO concentration correlates with emigration of WBCs from the vasculature. These findings support the hypothesis that activation of peripheral WBCs is an early step in the pathogenesis of acute laminitis.