Fulminant hepatic failure in non-Hodgkin’s lymphoma

Abstract

Summary Two patients with fulminant hepatic failure presenting during the course of non-Hodgkin’s lymphoma are described. One patient had no previous history of lymphoma whereas in the other a small bowel lymphoma had recently been diagnosed. Both patients had histological evidence of lymphomatous infiltrate in the liver and no other cause for the fulminant hepatic failure could be found. Neither patient responded to treatment with corticosteroids: the cautious use of combined chemotherapy may be justified.