CHARACTERISTICS OF ADENOSINE TRIPHOSPHATASE RELEASE FROM PORCINE AND HUMAN NORMAL BLADDER

Abstract

The characteristics of ATP release from porcine and human bladders are similar and, therefore, the pig is a good model for humans. The main source of ATP release is urothelium from predominantly nonneuronal sources. This study supports a sensory role for ATP. An increased role for this purinergic neurotransmission may result in functional motor as well as sensory bladder disorders.