Phrymarolin-I, a Novel Lignan from Phryma leptostachya L.

Abstract

A novel lignan, named phrymarolin-I, has been isolated from Phryma leptostachya L. The structure (I) for phrymarolin-I represents the first example of a lignan characterized by a l,2-dioxygenated-3,7-dioxabicyclo[3.3.0]octane ring. Its stereochemistry was determined from NMR spectra.