Experimental Biology and Medicine · 1967 · 22 citations · 0 references
Life SciencesImmunologyInfectious DiseasesAdaptive ImmunityImmunizationImmunology Of Infectious DiseasesBacterial ImmunologyHumoral Immune ResponsesHumoral ImmunityMucosal Immune SystemMucosal ImmunityMucosal ImmunizationAnimal ImmunizationField StudiesHumoral Immune DefenseHumoral Immunity To BacteriaIntestinal Mucosal ImmunityMucosal Immune Responses To PathogensMucosal Immunity To BacteriaMucosal Immunization Against Enteric Pathogens
Choleragen, administered paren-terally, immunized adult rabbits against intestinal challenge with either living cholera vibrios or with choleragen. A degree of resistance against choleragen could be passively transferred by serum to infant rabbits. These results suggest that choleragen offers promise as an effective immunogen against cholera although additional study is needed before any field studies can be performed.