Innovative therapeutic approach: Sequential treatment with plasma exchange and eculizumab in a pregnant woman affected by atypical hemolytic-uremic syndrome

Terminal Complement Inhibitor Eculizumab in Atypical Hemolytic–Uremic Syndrome

Christophe Legendre, Christoph Licht, Petra Muus et al. · New England Journal of Medicine · 2013 · 1.6K citations · Full text

Medicine, Hematology, Pharmacotherapy +17

Relative Role of Genetic Complement Abnormalities in Sporadic and Familial aHUS and Their Impact on Clinical Phenotype

Marina Noris, Jessica Caprioli, Elena Bresin et al. · Clinical Journal of the American Society of Nephrology · 2010 · 1K citations · Full text

Life Sciences, Genetics, Human Genetics +13

Genetics of HUS: the impact of MCP, CFH, and IF mutations on clinical presentation, response to treatment, and outcome

Jessica Caprioli, Marina Noris, Simona Brioschi et al. · Blood · 2006 · 730 citations · Full text

Life Sciences, Genetics, Molecular Genetics +12

Pregnancy-Associated Hemolytic Uremic Syndrome Revisited in the Era of Complement Gene Mutations

Fádi Fakhouri, Lubka T. Roumenina, François Provôt et al. · Journal of the American Society of Nephrology · 2010 · 464 citations

Life Sciences, Genetics, Hematology +14

The management of pregnancy in paroxysmal nocturnal haemoglobinuria on long term eculizumab

Richard Kelly, Louise Arnold, Stephen J. Richards et al. · British Journal of Haematology · 2010 · 132 citations · Full text

Medicine, Obstetrics, Pharmacotherapy +8