Pre‐transplant elevations of interleukin‐12 and interleukin‐10 are associated with acute rejection after renal transplantation

Abstract

Pre-transplant elevations of IL-12 and, unexpectedly, IL-10 are associated with acute rejection after cadaveric renal transplantation and may be useful in predicting which patients are at increased immunological risk at the time of transplantation. Further studies are necessary to assess the role of occult systemic inflammation in contributing to poor outcomes after transplantation.