American Journal of Hematology · 2003 · 34 citations · 7 references
MedicineOncologyPathologyCytopathologyHematopathologyNeoplasiaHematologic MalignanciesHematopoietic NeoplasmsLymphoid TumorsMesenchymal TumorsPediatric TumorsSoft Tissue SarcomasFacial Nerve Involvement By NeoplasmLeukemia PathologyMyeloid NeoplasmsMyeloid Sarcoma
Granulocytic sarcoma or chloroma is a tumor composed of myeloblast or monoblast. These tumors may be found in any location of the body and occur in 5% of acute myeloid leukemia (AML) cases and are more common in pediatric patients. In this report we describe the case of a 27-year-old male who developed lower motor neuron seventh nerve palsy followed by swelling of the parotid gland. Fine-needle aspiration cytology (FNAC) of the soft tissue swelling revealed scattered blasts, and peripheral smear and bone marrow aspirate examination suggested AML. This is a rare presentation of a granulocytic sarcoma leading to a diagnosis of AML.
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Harrison's Principles of Internal Medicine
Darlene Freeman · JAMA · 2001 · 1.6K citations
Granulocytic sarcoma preceding acute leukemia.A report of six cases
John R. Krause · Cancer · 1979 · 211 citations