IEEE Transactions on Biomedical Circuits and Systems · 2011 · 14 citations · 16 references
Apd-based Pet ImagingHigh Accuracy MultichannelEngineeringPet-mriAdvanced ImagingBiomedical EngineeringHold CircuitImage SensorPositron Emission TomographyReadout ChainComputational ImagingPhoton-counting Computed TomographyRadiation ImagingNuclear MedicineRadiologyHealth SciencesElectrical EngineeringMedical ImagingComputer EngineeringSignal ProcessingElectronic ImagingBioelectronicsBiomedical Imaging
This paper presents the design of a high accuracy multichannel peak detect and hold (PDH) circuit. This PDH measures the energy of an event and is one part of a readout chain for avalanche photo diodes (APD)-based positron emission tomography (PET) imaging. The circuit is designed in a 0.35μm CMOS process. The proposed PDH is dedicated to ultra low amplitude, large amplitude range from several tens millivolts to 1.1 V, and fast peaking time (190 ns) semi-Gaussian pulses. The two-phase technique has been used to cancel the major error source of the classical CMOS PDH: offset. A two-gain OTA is applied to minimize the DC error. A peak error less 1% for a small input signal (amplitude is between 40 mV and 300 mV) and a peak error less than 0.2% for a large input signal (amplitude is between 300 mV and 1.1 V) have been obtained from test. The area of a PDH is equal to about 200 μm × 40 μm. In our PDH system, the drop rate is negligible.
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Performance Evaluation of the LabPET APD-Based Digital PET Scanner
Mélanie Bergeron, J. Cadorette, Martin Lepage et al. · IEEE Transactions on Nuclear Science · 2009 · 153 citations
Gary D. Hutchins, Michael A. Miller, V.C. Soon et al. · ILAR Journal · 2008 · 86 citations
Positron Emission Tomography, Imaging Biomarkers, Engineering +14