Epithelioid Angiosarcoma of the Adrenal Gland. Report of a Case and Review of the Literature

Abstract

Case report: We present a case of 55 year old man with primary epitheloid angiosarcoma of the right adrenal gland and a review of the literature in an attempt to better define the clinical and pathological features of these neoplasms and their biologic potential. Immunohistochemical analyses were performed using endothelial cell markers (CD31, CD34 and Factor VIII). The analyses showed focal positivity of tumor cells, especially CD31 and weak focal positivity for tumor cells of Cytokeratin 18. The review of the literature showed 32 cases described up-to-date.