Inhibition of hyphae formation and<i>SIR2</i>expression in<i>Candida albicans</i>treated with fresh<i>Allium sativum</i>(garlic) extract

Chen Fei Low, Pei Pei Chong, Phelim Voon Chen Yong, Crystale Siew Ying Lim, Zaid Ahmad, Fauziah Othman

Journal of Applied Microbiology · 2008 · 49 citations · 18 references

Abstract

Hyphal production is an essential virulence determinant of C. albicans for invasive infections, therefore garlic and its constituents can be effective not only against colonizing C. albicans strains present in mucosal infections, but also virulent strains causing systemic or invasive candidiasis.

References

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