Cyclooxygenase-2 selective inhibitors aggravate kainic acid induced seizure and neuronal cell death in the hippocampus

Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation.

Yael Gavrieli, Yoav Sherman, Shmuel A. Ben‐Sasson · The Journal of Cell Biology · 1992 · 9.5K citations · Full text

Dna Damage, Apoptosis, Dna Analysis +16

Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2

Masahiko Tsujii, Raymond N. DuBois · Cell · 1995 · 2.3K citations · Full text

Inflammation, Tumor Microenvironment, Cell Adhesion +13

Cyclo-Oxygenase-2 Gene Expression in Neurons Contributes to Ischemic Brain Damage

Shigeru Nogawa, Fangyi Zhang, M. Elizabeth Ross et al. · Journal of Neuroscience · 1997 · 719 citations · Full text

COX-2, a synaptically induced enzyme, is expressed by excitatory neurons at postsynaptic sites in rat cerebral cortex.

Walter E. Kaufmann, Paul Worley, Jodi A. Pegg et al. · Proceedings of the National Academy of Sciences · 1996 · 590 citations · Full text

Synaptic Transmission, Neurotransmitter, Induced Enzyme +26

Cyclooxygenase-2 inhibition prevents delayed death of CA1 hippocampal neurons following global ischemia

Masaki Nakayama, Koichi Uchimura, Raymond L. Zhu et al. · Proceedings of the National Academy of Sciences · 1998 · 345 citations · Full text