Human Colostrum and Serum Contain Antibodies Reactive to the Intimin-Binding Region of the Enteropathogenic Escherichia coli Translocated Intimin Receptor

Abstract

The intimin-binding region of Tir (Tir-M) is the immunodominant region of the polypeptide in humans. Both serum IgG-class and colostrum IgA-class antibodies reacted predominantly with the Tir-M domain.