Concepedia

Diagnosis of Homozygous α-Thalassemia in Cultured Amniotic-Fluid Fibroblasts

Vivian Wong, Ho Kei, D. Todd, Mitchell S. Golbus, Andrée M. Dozy, Yuet Wai Kan

New England Journal of Medicine · 1978 · 27 citations · 9 references

DOI

Concepts

Abstract

THE α-thalassemias in Asian populations are primarily caused by deletion of the α-globin structural genes.1 2 3 4 5 6 In the fatal condition of homozygous α-thalassemia associated with hydrops feta...

References

9

Gene deletion as the cause of α thalassaemia: Genetic lesion in homozygous α thalassaemia (hydrops fetalis)

John M. Taylor, Andrée M. Dozy, Yuet Wai Kan et al. · Nature · 1974 · 230 citations

, , +14

Gene deletion as the cause of α thalassaemia: The severe form of α thalassaemia is caused by a haemoglobin gene deletion

Sergio Ottolenghi, W. George Lanyon, John Paul et al. · Nature · 1974 · 220 citations

, , +15

ALPHA‐ AND BETA‐THALASSEMIA IN THAILAND*

Prawase Wasi, S Na-Nakorn, S. Pootrakul et al. · Annals of the New York Academy of Sciences · 1969 · 195 citations

, , +10

Identification of a Nondeletion Defect in α-Thalassemia

Yuet Wai Kan, Andrée M. Dozy, Richard F. Trecartin et al. · New England Journal of Medicine · 1977 · 193 citations

, , +11

Deletion of α-globin genes in haemoglobin-H disease demonstrates multiple α-globin structural loci

Yuet Wai Kan, A M Dozy, Harold Varmus et al. · Nature · 1975 · 163 citations

, , +9