PubMed · 1978 · 32 citations · 15 references
Veterinary MedicineBiochemistryToxicologyAquatic ToxicologyHeavy Metal ToxicologyMitochondrial BiologyHeavy Metal BioaccumulationHeavy Metal ContaminationHeavy Metal MetabolismMetal ToxicityMitochondrial PhysiologyTrace Element MetabolismBiological Uptake Of Trace MetalsMetal Ion TransportTrace Metal BioaccumulationTrace Metal HomeostasisTrace Metal Toxicity
Abstract 1. The uptake and effects of Ca 2+ , Mn 2+ , Zn 2+ and Cu 2+ in fish liver mitochondria was studied. 2. Ca 2+ and Mn 2+ were found to be taken up by an energy-dependent process similar to that described for rat liver mitochondria. 3. Zn 2+ was taken up to a very limited extent, but caused very strong inhibition of respiration. 4. Cu 2+ was taken up by an energy-independent process, which stimulated K + uptake. 5. The implications of these findings are discussed in the context of heavy metal pollution.
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