Isolation of Notoamide E, a Key Precursor in the Biosynthesis of Prenylated Indole Alkaloids in a Marine-Derived Fungus, <i>Aspergillus</i> sp.

Abstract

Notoamide E was identified to be a short-lived precursor in the biosynthesis of prenylated indole alkaloids in the mussel-derived Aspergillus sp. In addition, the feeding experiment of the (13)C-labeled notoamide E afforded structurally novel metabolites.