Concepedia

Human β‐defensins and toll‐like receptors in the upper airway

Sofie Claeys, T. De Belder, Gabriële Holtappels, Philippe Gevaert, Bruno Verhasselt, Paul Van Cauwenberge, Claus Bachert

Allergy · 2003 · 123 citations · 34 references

DOI

Abstract

These results demonstrate a strong defensin expression in tonsillar tissue compared with nasal and paranasal mucosa and adenoids. Toll-like receptor expression in all these tissues illustrates a possibly important immunological sentinel function of upper airway mucosa.

References

34

Peptidoglycan- and Lipoteichoic Acid-induced Cell Activation Is Mediated by Toll-like Receptor 2

Ralf Schwandner, Roman Dziarski, Holger Wesche et al. · Journal of Biological Chemistry · 1999 · 1.7K citations · Full text

Isolation and Characterization of Human μ-Defensin-3, a Novel Human Inducible Peptide Antibiotic

Jürgen Harder, Joachim Bartels, Enno Christophers et al. · Journal of Biological Chemistry · 2001 · 1.3K citations · Full text

Differential Alteration in Intestinal Epithelial Cell Expression of Toll-Like Receptor 3 (TLR3) and TLR4 in Inflammatory Bowel Disease

Elke Cario, Daniel K. Podolsky · Infection and Immunity · 2000 · 1.2K citations · Full text

Lipopolysaccharide Activates Distinct Signaling Pathways in Intestinal Epithelial Cell Lines Expressing Toll-Like Receptors

Elke Cario, Ian M. Rosenberg, Steven L. Brandwein et al. · The Journal of Immunology · 2000 · 750 citations

Production of β-defensins by human airway epithelia

Pradeep K. Singh, Hong Peng Jia, Kerry Wiles et al. · Proceedings of the National Academy of Sciences · 1998 · 572 citations