Brief Episodes of Intracranial Hypertension and Cerebral Hypoperfusion Are Associated With Poor Functional Outcome After Severe Traumatic Brain Injury

Abstract

This study demonstrates that the number of brief 5-minute episodes of ICH and CH is predictive of poor outcome after severe TBI. This finding has important implications for management paradigms which are currently targeted to treatment rather than prevention of ICH and CH. This study demonstrates that these brief episodes may play a significant role in outcome after severe TBI.