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Optimization of on-line solid phase extraction and HPLC conditions using response surface methodology for determination of WM-5 in mouse plasma and its application to pharmacokinetic study

BiochemistryGas ChromatographyResponse Surface MethodologyMedicineBioanalysisMass SpectrometryMouse PlasmaAnalytical ChemistryLiquid ChromatographyClinical ChemistryChromatographic AnalysisPharmacologyHplc ConditionsPharmacokineticsChromatographyDrug Analysis