Journal of the American Medical Association · 1948 · 52 citations · 26 references
Veterinary MedicineInfectious DiseasesInfectious Disease EpidemiologyInfectious Disease PathologyVirologyViral HepatitisViral InfectionsBlood-borne VirusesBloodborne ExposureInfectious HepatitisParenteral ExposureViral Hepatitis PathogenesisViral Hepatitis Transmission
The danger of accidentally transmitting disease from one person to another by means of a common hypodermic syringe has generally been looked on as remote. This is particularly true when dealing with apparently healthy persons. In fact, until recently, syphilis and malaria were the only common infections which were known to be readily transmitted in this manner. With the widespread and frequent use of syringes in the modern practice of medicine, the demonstration that another disease, virus hepatitis, may be so transmitted becomes a matter of considerable importance. It has now been experimentally demonstrated that virus hepatitis, including both the infectious or epidemic and the homologous serum type, may be transmitted to human beings by the parenteral injection of infected serum.<sup>1</sup>As little as 0.01 cc. of serum has been sufficient to produce the disease.<sup>2</sup>The filterable agent is present in the blood during botn the preicteric and
26