Development and progression of nephropathy in type 2 diabetes: The United Kingdom Prospective Diabetes Study (UKPDS 64)

Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33)

The Lancet · 1998 · 20.1K citations

Medicine, Endocrinology, Pharmacotherapy +13

Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34)

The Lancet · 1998 · 8.3K citations

Medicine, Endocrinology, Pharmacotherapy +17

Effects of Losartan on Renal and Cardiovascular Outcomes in Patients with Type 2 Diabetes and Nephropathy

Barry M. Brenner, Mark E. Cooper, Dick de Zeeuw et al. · New England Journal of Medicine · 2001 · 7.5K citations · Full text

Pharmacy, Pharmacology, Pharmacotherapy +17

Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 38

BMJ · 1998 · 6.7K citations · Full text

Medicine, Internal Medicine, Pharmacotherapy +16

The Effect of Angiotensin-Converting-Enzyme Inhibition on Diabetic Nephropathy

Edmund J. Lewis, Lawrence G. Hunsicker, Raymond P. Bain et al. · New England Journal of Medicine · 1993 · 5.4K citations

Medicine, Nephrology, Pharmacology +13