Three-Dimensional Spheroidal Culture Visualization of Membranogenesis of Bruch's Membrane and Basolateral Functions of the Retinal Pigment Epithelium

Abstract

This model provides direct views of epithelialization processes involving elastogenesis and functions at the basolateral side such as lipoprotein deposition and may elucidate not only unknown epithelial behaviors but also the pathogenesis of RPE-related diseases.